Recent Publications
(Written by MU reseachers)

Prostate Project
Immunity Project
Ischemia Project
Plant Core
Analytical Core

Prostate Project

Dietary genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ER alpha KO, mice. Day JK. Besch-Williford C. McMann TR. Hufford MG. Lubahn DB. MacDonald RS. Nutrition & Cancer-An International Journal. 39(2):226-232, 2001.

Genistein Alters DNA Methylation Patterns in Mice. J. Kevin Day, Andrew M. Bauer, Charles desBordes, Yi Zhuang, Byung-Eun Kim, Leslie G. Newton, Vedika Nehra, Kara M. Forsee, Ruth S. MacDonald, Cynthia Besch-Williford, Tim HG Huang and Dennis B. Lubahn. Submitted to Journal of Nutrition 2002.

Expression of urokinase plasminogen activator and receptor in conjunction with ets family and AP-1 complex transcription factors in high grade prostate cancers. Gavrilov, D., Kenzior, O., Evans, M., Calaluce, R., and Folk, W.R. European Journal of Cancer, 37, 1033-1040 (2001).

Cell-Type Dependence of 17b-Estradiol Binding and Transactivation of Human Estrogen Receptor a and Estrogen Receptor b Xiaohui Yuan, Edward M. Curran, Peter J. Ansell, Wade V. Welshons, and Dennis B. Lubahn. Submitted to Molecular Endocrinology.

17b-Estradiol Binding and Transactivation Properties of Human Estrogen Receptor a and Estrogen Receptor b Heterodimers in an ER-Negative MCF-7 Cell Line. Xiaohui Yuan, Edward M. Curran, Wade V. Welshons, and Dennis B. Lubahn. Submitted to Molecular Endocrinology.

Enzymatic Syntheses of Radiolabeled 4-Hydroxylated Catechol Estrogens: Protein Binding Studies in WT, ERaKO and ArKO Mice Tissues Brian J. Philips, Pete J. Ansell, Edward M. Curran, Venkataseshu Ganjam, George E. Rottinghaus, Wade V. Welshons and Dennis B. Lubahn. Submitted to Journal of Biological Chemistry.

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Immunity Project

EM. Curran, C Besch-Williford, NJ Vernetti, AJ Saporita, IV Palmer, MG. Hufford, D Mark Estes, Dennis B Lubahn. The Endocrine Society's 82nd Annual Meeting in Toronto, Canada. June 21-24, 2000. Natural Killer Cells Express ERa, not ERb, and Have Altered Activity in ER-aKO Mice.

E . Curran, NJ Vernetti, MG. Hufford, D Mark Estes, Dennis B Lubahn. Estrogen and Natural Killer Cell Function in ERaKO/SCID/C57BL6J Mice. Proceedings of the Era of Hope. Department of Defense Breast Cancer Research Program Meeting in Atlanta, GA. June 8-11, 2000, page 497, Volume II.

Curran E., L. Berghaus, N. Vernetti, A. Saporita, D. Lubahn, and D.M. Estes. 2001. Natural Killer Cells Express Estrogen Receptor-(alpha) and Estrogen Receptor-(beta) and Can Respond to Estrogen Via a Non-Estrogen Receptor-(alpha) Mediated Pathway" In press. Cellular Immunology.

Curran E., Vernetti N., Judy B., Saporita A., Lubahn D and Estes DM. Regulation of NK cell activity by 17-beta estradiol and the anti-estrogen ICI 182,780 in wild type and estrogen receptor-alpha deficient mice. In preparation.

Curran E., Vernetti N., Judy B., Newton L., McDonald R., Lubahn D, Franklin C. and Estes DM. Dietary phytoestrogens promote susceptibility to mycobacterial infection via down modulation of interferon gamma production. In preparation.

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Ischemia Project

Sun AY, Simonyi A, and Sun GY (2002) The "French paradox" and beyond: Neuroprotective effects of polyphenols. Free Radical Biol. & Med. (in press)

Xu J, Weng YI, Krugh BW, Weisman GA, and Sun GY. (2002) Role of PKC and MAPK on cPLA2 in primary astrocytes. (J. Neurochem, under revision).

Simonyi A, Woods D, Sun AY, and Sun GY (2002) Grape polyphenols inhibit chronic ethanol-induced COX-2 mRNA expression in rat brain. Alcoholism: Clin & Expt Res., (in press).

Shen S., Fritsche K, Donato R., and Sun GY (2002) IFNg induces type II NOS in microglial cells: Cross-talk with NF-kB through a PKC-dependent ERK1/2 pathway. J. Neurochem. (under revision)

Wang Q, Xu J, Woods D, Rottinghaus G, Simonyi A, Sun GY and Sun AY. (2002) Resveratrol protects against cerebral ischemic injury in gerbils. Brain Research, in preparation.

Zheng Q, Binek J, and Sun GY. (2002) Polyphenolic compounds inhibit IFNg-induced iNOS in BV2 microglial cells.

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Plant Core

Applequist, W. L. Proposal to reject the name Lavandula spica L. Taxon, in press.

Applequist, W. L. Corrections to the nomenclature of Matricaria and Tripleurospermum. Taxon, in press.

Miller, J. S., and W. L. Applequist, in prep. The importance of specimens in authentication of identity of species used as ingredients in botanical dietary supplements.

Applequist, W. L., in prep. Root anatomy of North American Ligusticum and Conioselinum species.

Applequist, W. L., in prep. Notes on the rhizome and root anatomy of some Actaea species.

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Analytical Core

Gray DE, Rottinghaus GE, Garrett HE, and Pallardy SG. Simultaneous determination of the predominant hyperforins and hypericins in St. John's Wort (Hypericum perforatum L.) by liquid chromatography J Assoc Off Analytical Chemists Int 83:944-949, 2000.

Gray DE, Roberts CA, Rottinghaus GE, Garrett HE, and Pallardy SG. Quantitation of root chicoric acid in purple coneflower by near infrared reflectance spectroscopy. Crop Sci 41:1159-1161, 2001.

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